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It is an event during which the membrane power in a cell is first increased and then decreases. It is a signature characteristic of many living cells, including muscle cells, neurons, and endocrin cells. Plant cells can also produce them. Neurons play the most important role in cell-tocell communications. in pancreas beta cell action potential is associated with hormone release. Plasma membrane is a type of ion channels with voltage-gated voltages for producing action potential. The channels remain closed as long as the potential of the membrane is near it's resting value of the cell . However, when the membrane potential rises then the channels are activated. When the channels become active, they permit an inward flow of sodium ions, which boosts their membrane voltage. The swift inward flow of sodium ions causes a change in the polarity of the membrane and , consequently, they disappear. After that potassium channels become activated , and the flow outward of the potassium ions due to which the membrane is returned to its neutral state. A transient negative shift referred to as the refractory phase prevents the return movement of the action potential. In animal cells , usually two types of these potentials exist, well-known, such as one that is generated from voltage-gated potassium channels and the second that occurs due to calcium channels that are voltage-gated.

Nearly all cells maintain an electrical difference between their external and internal environments. The voltage of the cell is measured in millivolts (mV). The typical voltage for an animal cell is -70mV. In the majority of cells minimal voltage fluctuations have been observed to occur , however in certain cells this is a typical characteristic. Certain cells also exhibit variations in the voltage, as the voltage fluctuates. The duration of these voltages can vary widely. In brain cells the down and up cycle of the action potential is executed in less then a thousandth of a second while in other cells, the cycles could take several seconds. The electrical property of an animal cell is dependent on its membrane structure. Cell membranes consist of layers of lipids and proteins. The lipid layer functions as an insulation.

Animal cells are all electrically polarized . They maintain the same voltage, also known as membrane potential. For dendrites, neurons, axons and cells' bodies possess distinct electrical characteristics. The most excitable component of neurons is the axon hillock, however, axons as well as cells body too can be stimulated. At the axon , the maximum resting power is -70 mV and the threshold potential is -55 mV. Synaptic signals to the neuron trigger depolarization which causes the membrane potential to increase or fall. The action potential is generated when enough depolarization has occurred and that membrane potential reaches a threshold value.

The action potential results of the work of voltage-gated Ion channels that are found in the plasma membranes of cells. The voltage-gated channel is actually a cluster composed of proteins that remain in plasma membrane and produces motion potential because it can cause positive feedback loop. Membrane power is responsible for managing the state of ion channels. The action potential is created when the positive feedback cycle gets full power. The duration and the amplitude are determined by the bio-physical properties associated with the voltage-gated ion channel. A variety of Ion Channels have been identified which generate positive feedback cycles that eventually result in the production of these potentials. Voltage-gated sodium-channels are involved with the creation of higher potentials , similar to those that result from nerve impulse. More slow ones such as those produced in muscles are controlled by the calcium Ion channels.The ones that have been the most extensively studied voltage -gated ion channels are the sodium ion channels participating in the speedier nerve impulse conduction.

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