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Donnie Darko Action Figure


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Donnie Darko Frank the Bunny 12Inch Talking Action Figure NECA from www.entertainmentearth.com
A process called an action potential happens where the membrane potential of a living cell first increases but then decreases. It is the characteristic property that is present in a wide variety of animal cells namely, muscles, neurons and endocrine cells. Certain plant cells also produce these. Neurons play a crucial role in cell-tocell communications. Beta cells of the pancreas action potential is associated with in the production of insulin. Plasma membranes contain a distinct type of voltage-gated ion channel for producing action potential. They remain closed in the event that membrane potentials are close to that of the cell . However when the membrane's voltage increases it becomes active. The channels that are active allow an inward flow sodium ions. This in turn increases the potential of membranes. The rapid flow inward of sodium ions changes the polarity of the membrane and as a result they become inactive. The potassium channels after that are active and it is a flow potassium ions . This causes the membrane returns back to its normal state. The transient shift in negative known as refractory is a way to stop back movement of the action potential. In animal cells generally two kinds of these voltages are understood, one that is generated due to the voltage-gated sodium channels and the other which is caused by voltage-gated calcium channels.

Most cells have the same voltage between their environment and their inside. The voltage of a cell is measured in millivolts (mV). The voltage of a typical animal cell is -70mV. For the vast majority of cells, no voltage fluctuations are known for their existence, but in some cells this may be a common feature. Cells can show oscillations between up and down when the voltage drops and increases. The time between these potentials vary throughout a vast range. In brain cells the up and down process of action possible are completed in less than thousandth of a second. In other types of cells the cycle may last for several seconds. The electrical properties of a cell in the animal kingdom is dependent on the membrane structure. The cell membrane is composed of an lipid layer and proteins. The lipid layer acts as an insulation.

Animal cells are all electrically polarized and maintain the same voltage, also called membrane potential. For the neurons, dendrites and cell body have different electrical characteristics. The most exuberant part of an neuron is its axon hillock, however the axon as well as the cell body also get excited. In the axon hillock, the resting potential is -70 mV and the threshold voltage is 55 mV. Synaptic inputs into the neuron cause depolarization, which causes the membrane potential to rise or fall. Action potentials are generated when enough depolarization is accumulated and the membrane voltage reaches a threshold value.

The action potential results of the activity of voltage-gated ion channels that are found in the plasma membranes of cells. The voltage-gated channel is in fact a collection of proteins that remains embedded in plasma membrane and produces an action potential in order to generate the positive feedback loop. Membrane current is responsible monitoring the status of ion channels. Action potential is generated during the time that the feedback cycle gets full power. The time and amplitude are dependent on the bio-physical properties associated with the voltage-gated ion channel. Many types of ion channels are available that are believed to generate positive feedback circuits that ultimately result in the production of these potentials. Voltage-gated sodium channels are involved in generation of faster impulses like nerve impulse. Lesser ones, such as those created by muscles cells are controlled by calcium Ion channels.The most extensively studied voltage-gated channel are sodium-ion channels that contribute to quicker nerve impulse conduction.

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