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Action potential is an event that occurs when the membrane potential of a cell first increases and then decreases. It is a characteristic property and characteristic of a lot of animal cells , including muscles, neurons, and endocrinological cells. Some plant cells also produce them. Neurons play a crucial function in cell-to-cell communication. In beta cells of pancreas action potential is connected with an insulin release. Plasma membranes are made up of a special kind of voltage-gated Ion channels creating action potential. These channels are shut at times when membrane potential is near that of the cell , but should the membrane potential increase it becomes active. Once the channels are open, they allow the flow of sodium ions. This in turn increases their membrane voltage. The rapid flow inward of sodium ions alters the membrane's polarity which causes them to cease to function. The potassium channels then become activated and they are able to flow outward of potassium ions . The result is that the membrane is returned back to its original position. A transient negative shift known as refractory periods prevents back moving of the action-potential. In animal cells , typically two types of these potentials exist, understood, one is generated because of voltage-gated sodium channels, and the second one that occurs due to calcium channels that are voltage-gated.

Nearly all cells maintain in a voltage differential between their surroundings and their interior. The cell's voltage is measured in millivolts (mV). The voltage of a typical animal cell is about -70 mV. In the majority of cells, low voltage variations are thought to occur however in some cells, this is a common feature. Certain cells can also exhibit fluctuations in voltage as the voltage drops and increases. The duration of these potentials fluctuate over a large range. In brain cells the down and up motion potential cycle are performed in less than a thousandth of a second. However, in other types of cells the cycles could take several seconds. The electrical characteristic of a cell in the animal kingdom is dependent upon the membrane structure. Cell membranes are composed of layers of lipids, and proteins. The lipid layer serves as an insulator.

Animal cells are all electrically polarized since they have an electric voltage which is known as membrane potential. In case of the neurons, dendrites and cells have distinct electrical characteristics. Most excitable portion of an individual neuron is the hillock. However, the axon and body too can be stimulated. In the axon hillock, the maximum resting power is -70 mV and the threshold voltage is -55 mV. The synaptic inputs to the neurons result in depolarization that causes the membrane potential to increase or decrease. The action potential is generated when enough depolarization is accumulated and the membrane potential crosses the threshold.

Action potential is the outcome that voltage-gated ion channels in the plasma membranes of cells. Ion channels that are voltage-gated are in fact a collection made of proteins. They remain within the plasma membrane. They produce actions potential due to the fact that it could be the cause of the positive feedback loop. Membrane potential is the main factor responsible for setting the parameters of these channels. Action potential is generated whenever the positive feedback proceeds with full intensity. The duration and intensity are determined by the biophysical properties of the voltage-gated ionchannels. Many types of ion channels are identified that generate positive feedback loops and eventually cause the creation of these potentials. Voltage-gated sodium-channels are involved in the creation of more powerful potentials similar to those generated by nerve impulse. Slower ones like those produced in muscle cells are mediated by the calcium Ion channels.The most studied voltage-gated channel are sodium ion networks that play an important role in higher speed nerve impulse transmission.

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