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Nearly all cells maintain an electrical difference between their internal and external environments. The voltage of the cell is measured in milli volts (mV). The voltage of a typical animal cell is about -70 mV. In the majority cells, minimal voltage fluctuations have been observed to take place, but in certain cells this is a regular characteristic. Some cells also display an up-and-down cycle as the voltage increases and declines. The duration of these potentials are variable across a variety of. In brain cells the down and up motion potential cycle are completed in less than thousandth of a second. In other cells, these cycle may last for several seconds. The electrical properties of a cell in the animal kingdom is dependent upon the membrane structure. The cell membrane is composed of layers of lipids, and proteins. The lipid layer acts as an insulation.
Animal cells are all electrically polarized and maintain a voltage difference called membrane potential. For neurons, axons, dendrites and the cell body possess different electrical properties. The area that is most excitable in neuron is called the axon hillock but axon and cell body too can be stimulated. The axon hillock's resting potential is 70 mV and the threshold potential is 55 MV. Synaptic messages to the brain result in depolarization that causes the membrane potential to increase or decrease. It is produced when enough depolarization builds up until the membrane potential reaches the threshold.
Action potential is the outcome by the action of voltage-gated channels found within the plasma membrane of cells. The voltage-gated channel is actually a group of proteins which remain in the plasma membrane. It generates an action potential since it could trigger a positive feedback loop. Membrane Potential is responsible for setting the parameters of Ion channels. Action potential is generated when the positive feedback circuit continues at its fullest. The duration as well as the magnitude are determined by the bio-physical properties of the voltage-gated Ion Channels. Several types of ion channels are identified that generate positive feedback cycles and ultimately lead to the generation of these potentials. They are involved in the generation of stronger potentials similar to those generated by nerve impulses. The slower ones, like those generated by muscles cells are controlled by calcium ion channels.The most thoroughly studied voltage-gated ion channels are the sodium ion channels which are involved in more rapid nerve impulse conduction.
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