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It is an event where the potential for the membrane of a cell increases but then decreases. This is a characteristic trait to a variety of animals, including neurons, muscle cells and cell types that are endocrine. Some plant cells also make them. Neurons play a vital part in cell-to cell communication. In the beta cells of the pancreas, the action potential is associated with releases of insulin. Plasma membranes feature a unique type of voltage-gated ion channels that are responsible for producing action potential. These channels remain closed when the membrane potential is near that of the cell but If the membrane's current potential rises it opens the channels. When they are opened, they allow an inward flow sodium ions which increases the membrane potential. The rapid flow inward of sodium ions causes a change in the membrane's polarity and consequently they are inactive. Following this, potassium channels become active and the flow outward sodium ions. Due to this, the membrane returns to its resting state. The transient shift in negative known as refractory duration prevents the reverse forward motion of an action potential. In animal cells generally two kinds of these are well-known, such as one of which is due to voltage-gated sodium channels and the other which occurs due to voltage-gated calcium channels.

Most cells have some degree of voltage variation between their internal and external environments. The cell's voltage is measured in milli volts (mV). The voltage of a typical animal cell is around -70 mV. In the majority cells, few voltage fluctuations are believed for their existence, but in some cells, this is a standard feature. Certain cells may also exhibit fluctuations in voltage as the voltage fluctuates. The duration of these voltages vary over a wide range. In brain cells the up and down sequence of action potentials are completed in a fraction of a millisecond of a second, whereas in other cell types, the cycles can take up to a few seconds. The electrical property of a cell in the animal kingdom depends on the membrane structure. Cell membrane is made up of the lipid layer as well as proteins. The lipid layer serves as an insulator.

All animal cells are electrically polarized . They maintain a voltage difference called membrane potential. For neurons, axonsand dendrites and cell bodies have different electrical characteristics. One of the most exciting parts of one's neuron's axon hillock, but the axon and the cell body too can be stimulated. At the axon hillock the resting potential is -70 mV and the threshold is 55 mV. Synaptic inputs into the neuron induce depolarization and cause the membrane potential to increase or fall. The action potential is generated when enough depolarization occurs and the membrane voltage reaches an upper limit.

The action potential results that voltage-gated ion channels within the plasma membrane of a cell. Ion channels that are voltage-gated are actually a cluster consisting of proteins that stay in the plasma membrane. This produces the action potential, which can create the positive feedback loop. Membrane potential plays a role in controlling the condition of these channels. Action potential is generated by the positive feedback cycle that is carried out at full force. Its duration and amplitude are determined by the bio-physical properties of the voltage-gated ion channels. Different types of ion channels are known to produce positive feedback processes that produce these potentials. Voltage-gated sodium channel are involved in the production of high-speed potentials similar to nerve impulse. Slower ones , like those made in muscles cells are controlled by calcium ion channels.The most researched voltage-gated ion channels are the sodium ion channels involved in the faster conduction of nerve impulses.

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