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Action potential is a phenomenon where the membrane potential of a living cell first increases but then decreases. It is a typical characteristic of many animal cells namely, muscles cells, nerve cells, and the endocrine cell. Some plant cells also make these. Neurons play an important role in cell-tocell communications. Beta cells of the pancreas the action potential is associated with hormone release. Plasma membrane has special type of voltage-gated ion channels for creating action potential. They remain closed whenever the membrane's potential remains close to that of the cell , but when the membrane's potential increases then the channels become active. When the channels are inactive, they permit the inward flow of sodium ions. This can increase the cell's membrane potency. The swift inward flow of sodium ions result in changing the polarity of the membrane which causes them to turn off. The potassium channels after that are activated and it is a flow of potassium ions , causing the membrane returns to its neutral state. A transient , negative shift known as refractory period prevents back movement of the action potential. In animal cells typically two kinds of these potentials are well-known, such as one that is caused due to voltage-gated sodium channels and another one that is generated by voltage-gated calcium channels.

The majority of cells have in a voltage differential between their interior and exterior environment. The voltage of a cell is measured in milli volts (mV). The voltage of a typical animal cell is -70mV. In the majority of cells few voltage fluctuations are believed to be present, however in some cells, this is a standard characteristic. Some cells also display upward and downward cycles as the voltage goes up and down. The duration of these voltages can be varied over a broad spectrum. In brain cells, the up and down cycle of the action potential is executed in less then a thousandth of a second, whereas in other types of cells the intervals may be prolonged to several seconds. The electrical capacity of a cell in the animal kingdom is influenced by the membrane structure. The cell membrane is composed of a layer of lipids and proteins. The lipid layer acts as an insulation.

All animal cells are electrically polarized due to an electric charge that is called membrane potential. In case of neurons, axons, dendrites and the body of the cell have distinct electrical properties. The area that is most excitable in an individual neuron is the hillock however axons and the cell body can also be stimulated. At the axon hillock the threshold potential for resting is -70mV and the threshold voltage is at -55 mgV. Synaptic connections to the nerve cause depolarization, causing the membrane potential to rise or fall. An action potential is created once enough depolarization is accumulated and the membrane voltage reaches an upper limit.

Action potential is the result on the activities of voltage-gated channels present in the plasma membrane of cells. A voltage-gated Ion Channel is actually a group made of proteins. They remain in the plasma membrane. This produces action potential because it can cause positive feedback loop. Membrane power is responsible for monitoring the status of Ion channels. Action potential is generated whenever the positive feedback takes place at full intensity. The time and amplitude of the action are controlled by the bio-physical characteristics of the voltage-gated ionchannels. A variety of Ion Channels have been identified which generate positive feedback cycles , which eventually create these potentials. They are involved in the production of high-speed potentials similar to those generated by nerve impulse. More slow ones such as those produced by muscles are controlled by calcium ion channels.The most rigorously researched voltage-gated Ion channels are the sodium-ion channels that contribute to greater speed of nerve impulse conduction.

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