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Action potential refers to an event in which the membrane voltage of a cell initially increases then decreases. It is a signature characteristic of a variety of animals, including muscles cells, neurons and the endocrine cell. Certain plant cells also produce them. Neurons play a vital part in cell-to cell communication. In pancreas beta cells, action potential is associated with that release of insulin. Plasma membrane has special type of voltage-gated ion channels for producing action potential. The channels remain closed at times when membrane potential is within its resting capacity of the cell but If the membrane's current potential rises then the channels will become active. If the channels are open, they allow an inward flow sodium ions which increases its membrane potential. The swift inward flow of sodium ions affects the polarity of the membrane and , consequently, they disappear. The potassium channels after that are activated and they are able to flow outward of the potassium ions , causing the membrane returns back to its original position. A temporary negative shift, known as the refractory phase prevents the return travel of the action potential. In animal cells generally two kinds of these are understood, one that is caused by the voltage-gated calcium channels, and the second one that can be produced by calcium channels that are voltage-gated.

A majority of cells experience an electrical difference between their external and internal environments. The voltage of the cell is measured in millivolts (mV). The typical voltage of an animal cell is -70mV. The majority of cells show low voltage variations are thought to occur however in some cells this is a typical feature. Some cells also show fluctuations in voltage as the voltage increases and declines. The duration of these voltages differ across a broad range. In brain cells the down and up motion potential cycle are completed in a fraction of a millisecond of a second, whereas in other cell types, the intervals may be prolonged to several seconds. The electrical function of an animal cell is dependent on its membrane structure. Cell membrane is comprised of the lipid layer as well as proteins. The lipid layer serves as an insulator.

All animal cells are electrically polarized . They maintain the voltage differential called membrane potential. For cells, neurons and axons, dendrites and cell body have different electrical properties. The most stimulated part of neurons is the axon hillock. However, the axon, dendrites, and cell body too can be stimulated. In the axon hillock, the resting voltage is -70 mV and the threshold voltage is -55 millivolts. Synaptic messages to the brain result in depolarization that causes the membrane potential to rise or decrease. An action potential is created once enough depolarization occurs and the membrane potential exceeds an upper limit.

Action potential is the outcome by the action of voltage-gated channels that are found in the plasma membranes of cells. The voltage-gated ion channel in fact a collection consisting of proteins that stay within the plasma membrane. They produce an action potential in order to cause an positive feedback loop. Membrane power is responsible for controlling the state of ion channels. The action potential is created during the time that the feedback cycle takes place at full intensity. Its duration and amplitude are dependent on the bio-physical properties associated with the voltage-gated ion channel. There are a variety of ion channel types that have been discovered that cause positive feedback loops and eventually create these potentials. These sodium channels are involved in the production of high-speed potentials , similar to those that result from nerve impulse. Lesser ones, such as those created in muscles cells are controlled by calcium Ion channels.The most intensively studied voltage-gated ion channels are the sodium ion channels that are involved in higher speed nerve impulse transmission.

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