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The action potential is a process during which the membrane power for a specific cell initially increases then decreases. It is the characteristic property of many animal cells including muscles, neurons and the endocrine cells. Some plant cells also produce them. Neurons play an important function in cell-to-cell communication. in pancreas beta cell action potentials are connected to the release of insulin. Plasma membrane has a particular type of voltage-gated ion channels that are responsible for creating action potential. The channels remain closed whenever the membrane's potential remains near the potential at rest of the cell . However, when the membrane's potential increases and the channels begin to open, they become active. When the channels become active, they permit an inward flow of sodium ions which increases the potential of membranes. The fast inward flow of sodium ions affects the polarity of the membrane and , in the process, stop functioning. In the following, potassium channels become activated , and the flow outward potassium ions , causing the membrane is returned to its neutral state. A transient negative shift known as refractory duration prevents the reverse motion of the potential. In the animal cell, generally two varieties of these possibles are identified, for instance, one which is triggered via voltage-gated channels, and another that is caused by calcium channels that are voltage-gated.

Nearly all cells keep in a voltage differential between the outside and inside. The voltage of a cell is measured in milli volts (mV). The typical voltage of an animal cell is -70mV. The majority of cells show minor voltage fluctuations are observed for their existence, but in some cells this is a regular feature. Certain cells can also exhibit variations in the voltage, as the voltage increases and declines. The time between these potentials vary over a wide range. In brain cells the down and up cycles of action potentials are completed in less that a thousandth of a second. However, in different types of cells, the cycle may last for several seconds. The electrical function of a cell in the animal kingdom is influenced by the membrane structure. Cell membranes are composed of the lipid layer as well as proteins. The lipid layer serves as an insulator.

Animal cells are all electrically polarized and maintain the voltage differential called membrane potential. In case of neuronal cells, axons and the cell body all have different electrical characteristics. The most excitable part of neuron is the axon hillock but axon and cell body too can be stimulated. The axon hillock's resting potential is 70 mV and the threshold is -55 mV. Synaptic stimulation to the neuron cause depolarization, which causes the membrane potential to increase or fall. A potential for action is created when enough depolarization is accumulated and the membrane potential reaches an upper limit.

The action potential results of activity of voltage-gated ion channels located in the plasma membrane of cells. The voltage-gated ion channel in fact a collection of proteins that remains embedded in the plasma membrane. It generates movement potential because it is able to result in a positive feedback loop. Membrane potential is accountable for controlling the state of Ion channels. Action potential is generated when the positive feedback cycle gets full power. The time and the intensity are controlled by the bio-physical characteristics associated with the voltage-gated ion channel. Different types of ion channels exist that can generate positive feedback and result in the production of these potentials. They are involved in the generation of higher-frequency potentials that mimic those of nerve impulse. These are the ones that are slower, similar to those found by muscle cells are mediated by calcium ion channels.The ones that have been the most extensively studied voltage -gated Ion channels are the sodium ion channels that are involved in higher speed nerve impulse transmission.

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