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The majority of cells have the same voltage between their internal and external environments. The voltage of the cell is measured in millivolts (mV). The typical voltage of an animal cell is -70 mV. In the majority of cells small voltage fluctuations are reported for their existence, but in some cells this is an expected characteristic. Certain cells can also exhibit the cycle of up and down as they increase and decrease in voltage. The duration of these voltages vary throughout a vast range. In brain cells, the up and down action potential cycle is completed in less than thousandth of a second. In other cells, these actions can last for a long time. The electrical properties of a cell in the animal kingdom depends on the membrane structure. Cell membrane is made up of layers of lipids, and proteins. The lipid layer acts as an insulation.
All animal cells are electrically polarized and maintain the difference in voltage called membrane potential. In case of neuronal cells, axons and cell body have different electrical properties. The area that is most excitable in neurons is the axon hillock, however, axons as well as cells body can also be excited. At the axon hillock the resting voltage is -70 mV and the threshold voltage is -55 millivolts. Synaptic messages to the brain result in depolarization causing the membrane potential to rise or decrease. It is produced when enough depolarization happens and the membrane voltage reaches a threshold value.
Action potential is the result in the function of voltage-gated channels within the plasma membrane of cells. The voltage-gated ion channel actually a group of proteins which remain in the plasma membrane. It produces action potential because it can give rise to the positive feedback loop. Membrane Potential is responsible for controlling the level of these channels. Action potential is generated when the feedback cycle goes on at full-speed. The duration as well as the magnitude are determined by the biophysical properties associated with the voltage-gated ion channel. Ion channels of various types are available that are believed to generate positive feedback cycles and ultimately create these potentials. The sodium channels that are voltage-gated participate in the creation of fast impulses like nerve impulse. These are the ones that are slower, similar to those found in the muscle cells are controlled by the calcium ion channels.The most studied voltage-gated Ion channels are the sodium ion channels that are involved in more rapid nerve impulse conduction.
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