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The majority of cells have an electric field between their surroundings and their interior. The voltage of the cell is measured in millivolts (mV). The typical voltage of an animal cell is -70mV. For the vast majority of cells, tiny voltage fluctuations are observed to occur however in some cells this may be a common feature. Some cells exhibit fluctuations in voltage as the voltage drops and increases. The duration of these voltages fluctuate over a large range. In brain cells the down and up cycle of action potential are completed in less than a thousandth of a second. However, in other cells, these actions can last for a long time. The electrical capacity of a cell in the animal kingdom depends on the membrane structure. The cell membrane is composed of an outer layer of lipids as well as proteins. The lipid layer serves as an insulator.
All animal cells are electrically polarized , as they sustain the difference in voltage called membrane potential. For cells, neurons and axons, dendrites and the body of the cell have distinct electrical properties. The most stimulated part of an individual neuron is the hillock but axon and cell body also become excited. At the axon hillock the threshold potential for resting is -70mV and the threshold is 55 mgV. Synaptic connections to the nerve result in depolarization which causes membrane potential to increase or decrease. A potential for action is created when enough depolarization happens and the membrane potential reaches a threshold value.
Action potential is the outcome from the voltage-gated channels that are found in the plasma membrane of cells. The voltage-gated channel is actually a cluster consisting of proteins that stay in plasma membrane and produces the action potential, which can create the positive feedback loop. Membrane Potential is responsible for control of the activity of ion channels. Action potential is generated by the positive feedback cycle that gets full power. The time and the intensity are determined by the bio-physical properties of the voltage-gated Ion Channels. Many kinds of ionchannels are known that produce positive feedback cycles and ultimately lead to the generation of these potentials. The sodium channels with voltage are involved in the creation of more powerful potentials similar to those generated by nerve impulse. Slower ones like those produced by muscle cells are mediated by the calcium ion channels.The most rigorously researched voltage-gated ion channels are the sodium ion networks that play an important role in faster nerve impulse conduction.
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