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Tulfo In Action Latest. Raffy tulfo in action, quezon city, philippines. Covering the activities and issues of the philippine government and private sectors

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Action potential refers to an event in which the membrane voltage of a cell initially increases but then decreases. It is a characteristic property of many animals, including muscles, neurons, and hormone-producing cells. Certain plant cells also produce these. Neurons play a very crucial part in cell-to cell communication. In the beta pancreas cells action potentials are associated with production of insulin. Plasma membranes contain a distinct type in voltage-gated, ion-channels that are used for creating action potential. These channels remain closed even when their membrane potential is within those of cells, however if the membrane potential increases then the channels will become active. When the channels open they permit an inward flow of sodium ions. This in turn increases that membrane's capacity. The fast inward flow of sodium ions can alter the polarity of the membrane which causes them to stop functioning. The potassium channels then become activated , and the flow outward of the potassium ions . Upon this, the membrane is returned to its resting state. The transient negative change known as refractory period prevents back running of the action kinetic. In animal cells , typically two types of these potentials exist, in existence, one of which is created through voltage-gated sodium channels, the other is caused by voltage-gated calcium channels.

Most cells have a voltage difference between their surroundings and their interior. The voltage of the cell is measured in millivolts (mV). The typical voltage for an animal cell is around -70 mV. In most cells, small voltage fluctuations are reported to occur , however in certain cells this can be a normal feature. Certain cells also exhibit upward and downward cycles as the voltage drops and increases. The time between these potentials can vary widely. In brain cells, the up and down process of action possible are accomplished in less than one thousandth of a second while in other types of cells the actions can last for a long time. The electrical ability of an animal cell is dependent upon the membrane structure. The cell membrane is composed of the lipid layer as well as proteins. The lipid layer functions as an insulator.

All animal cells are electrically polarized . They maintain the same voltage, also known as membrane potential. In case of cells, neurons and axons, dendrites and the cell body all have different electrical properties. The most exuberant part of neuron is the axon hillock. However, the axon and body too are excited. At the axon , the resting voltage is -70 mV and the threshold voltage is 55 mgV. Synaptic connections to the nerve trigger depolarization which causes the membrane potential to increase or decrease. An action potential is created once sufficient depolarization takes place and the membrane voltage reaches a threshold value.

The action potential results of the work of voltage-gated Ion channels which are located within the plasma membrane of cells. A voltage-gated ion channel is actually a cluster of proteins that are embedded in plasma membranes and generates an action potential since it could give rise to an positive feedback loop. Membrane voltage is responsible for setting the parameters of Ion channels. Action potential is generated in the event that the positive feedback process runs at full speed. The time and amplitude are determined by the biophysical properties associated with the voltage-gated ion channel. Numerous types of ion-channels are identified that generate positive feedback cycles that eventually cause the creation of these potentials. Voltage-gated sodium-channels are involved in the generation of stronger impulses like nerve impulses. The slower ones, like those generated by muscles cells are controlled by the calcium ion channels.The the most intensely studied voltage-gated Ion channels are the sodium ion channels that are involved in the speedier nerve impulse conduction.

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