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Action potential is an occurrence in which the membrane voltage of a particular cell increases then decreases. It is a characteristic feature of several animals, including muscles cells, nerve cells, and endocrinological cells. Certain plant cells also produce these. Neurons play the most important function in cell-to-cell communication. In beta cells of pancreas action potentials are linked with an insulin release. Plasma membrane is a type of voltage-gated ion channels for creating action potential. These channels remain closed even when their membrane potential is close to an equilibrium potential for the cell . However, when the membrane's potential increases then the channels are activated. As the channels become open, they permit an inward flow sodium ions which increases that membrane's capacity. The rapid inward flow of sodium ions causes a change in the membrane's polarity and , consequently, they become inactive. After this, potassium channels get activated and you can see an outward movement of the sodium ions. Due to this, the membrane returns back to its normal state. The transient negative change known as refractory interval prevents further running of the action kinetic. In animal cells generally two types of these potentials exist, described, for instance, one which is produced because of voltage-gated sodium channels and another one that is generated by voltage-gated calcium channels.

Nearly all cells show an electrical difference between their internal and external environments. The voltage of a cell is measured in millivolts (mV). The typical voltage of an animal cell is -70mV. In majority of cells very tiny voltage fluctuations are observed to take place, but in certain cells this is a usual characteristic. Cells can show oscillations between up and down when the voltage increases and declines. The duration of these potentials fluctuate over a large range. In brain cells the down and up motion potential cycle are performed in less than a thousandth of a second. In other cells, the sequences can take as long as a couple of seconds. The electrical function of a cell in the animal kingdom is dependent on the membrane structure. The cell membrane is composed of one layer of lipids along with proteins. The lipid layer functions as an insulation.

Animal cells are all electrically polarized as they maintain the same voltage, also known as membrane potential. In case of the neurons, dendrites as well as the cell body have various electrical properties. The most excitable component of neuron is called the axon hillock, but the axon and the cell body also become excited. The axon hillock's maximum resting power is -70 mV and the threshold is 55 mgV. Synaptic stimulation to the neuron lead to depolarization. This causes the membrane potential to increase or fall. An action potential is created once enough depolarization develops until that membrane potential reaches the threshold.

Action potential is the result by the action of voltage-gated channels which are located within the plasma membrane of a cell. A voltage-gated Ion Channel is in fact a collection of proteins which remain in the plasma membrane. This produces an action potential in order to be the cause of a positive feedback loop. Membrane power is responsible for setting the parameters of Ion channels. Action potential is generated when the positive feedback cycle gets full power. Its duration and amplitude are determined by the biophysical properties of the voltage-gated ion channels. Numerous types of ion-channels are recognized that create positive feedback cycles and ultimately produce these potentials. Voltage-gated sodium channels are involved in the generation of stronger potentials , similar to those that result from nerve impulse. Lesser ones, such as those created in muscle cells are mediated by the calcium Ion channels.The most studied voltage-gated Ion channels are sodium ion channels which are involved in higher speed nerve impulse transmission.

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