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Nia 114 Multi Action


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An action potential occurs where the potential for the membrane of a cell increases before decreasing. It is a typical characteristic and characteristic of a lot of animal cells namely, muscles, neurons and endocrin cells. Certain plant cells also produce these. Neurons play an extremely important part in cell-to cell communication. In the beta cells of the pancreas, action potential is connected with that release of insulin. Plasma membranes contain a distinct type of voltage-gated ion channel for creating action potential. The channels remain closed in the event that membrane potentials are near what is the limit of the cell but if the membrane potential increases then the channels are activated. When the channels are inactive, they permit an inward flow sodium ions. This increases cell membrane power. The swift inward flow of sodium ions causes a change in the membrane's polarity and consequently they disappear. After that potassium channels become activated , and the flow outward of the potassium ions , causing the membrane is returned to its original state. A transient negative shift referred to as refractory periods prevents back travel of the action potential. In animal cells typically two kinds of these potentials can be in existence, one which is produced by voltage-gated sodium channels and the other which is caused by voltage-gated calcium channels.

The majority of cells exhibit the same voltage between the outside and inside. The voltage of a cell is measured in millivolts (mV). The typical voltage of an animal cell is about -70 mV. In the majority of cells, tiny voltage fluctuations are observed for their existence, but in some cells this is a typical feature. Some cells exhibit up and down cycles as the voltage goes up and down. The time between these potentials vary over a wide range. In brain cells, the up and down cycles of action potentials are completed in less than thousandth of a second. In other types of cells , processes can last several seconds. The electrical activity of an animal cell is dependent on its membrane structure. The cell membrane is composed of the lipid layer as well as proteins. The lipid layer functions as an insulator.

All animal cells are electrically polarized and maintain an electric voltage which is known as membrane potential. For neurons, axons, dendrites as well as the cell body have various electrical properties. Most excitable portion of neurons is the axon hillock however axons and the cell body also get excited. In the axon hillock, the threshold potential for resting is -70mV and the threshold potential is at -55 MV. Synaptic stimulation to the neuron lead to depolarization. This causes the membrane potential to increase or fall. Action potential is produced when enough depolarization occurs and the membrane potential exceeds a threshold value.

Action potential is the result by the action of voltage-gated channels in the plasma membrane of cells. A voltage-gated , ion channel is in fact a collection of proteins which remain inside the plasma membrane. These proteins produce action potential because it can produce a positive feedback loop. Membrane current is responsible controlling the condition of these channels. Action potential is generated when the feedback cycle goes on at full-speed. The frequency and duration are dependent on the bio-physical properties of the voltage-gated Ion Channels. A variety of Ion Channels have been discovered that cause positive feedback mechanisms and result in the production of these potentials. The sodium channels that are voltage-gated participate in the creation of fast potentials that mimic those of nerve impulses. These are the ones that are slower, similar to those found by muscle cells are controlled by the calcium ion channels.The most rigorously researched voltage-gated Ion channels are the sodium-ion channels that contribute to higher speed nerve impulse transmission.

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