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It is an event during which the membrane power of a cell first increases then decreases. It is a signature characteristic to a variety of living cells, including muscles, neurons and endocrinological cells. Some plant cells also make these. Neurons play an important part in cell-to cell communication. In pancreas beta cells, action potential is linked to production of insulin. Plasma membranes contain a distinct type in voltage-gated, ion-channels that are used for creating action potential. The channels are closed at times when membrane potential is close to it's resting value of the cell . However when the membrane's voltage increases then the channels open. When the channels open they allow for an inward flow sodium ions. This can increase the cell's membrane potency. The rapid flow inward of sodium ions alters the polarity of the membrane and they turn off. The potassium channels after that are activated and it is a flow potassium ions . In the process, the membrane returns to its normal state. The transient negative change known as refractory interval prevents further traveling of the action voltage. In animal cells , two kinds of these potentials can be well-known, such as one that is generated because of voltage-gated sodium channels, the other is caused by calcium channels that are voltage-gated.

Nearly all cells show an electrical difference between the outside and inside. The cell's voltage is measured in milli volts (mV). The voltage of a typical animal cell is -70mV. In the majority of cells, small voltage fluctuations are reported to occur but in some cells this is an expected feature. Some cells also display the cycle of up and down as the voltage drops and increases. The duration of these potentials fluctuate over a large range. In brain cells, the up and down cycle of action potential are completed in less than thousandth of a second. In other types of cells the cycle may last for several seconds. The electrical property of an animal cell is dependent on the membrane structure. Cell membrane is made up of two layers of lipids and proteins. The lipid layer acts as an insulator.

Animal cells are all electrically polarized due to a voltage difference known as membrane potential. In case of dendrites, neurons, axons and cell bodies have different electrical characteristics. The most stimulated part of an individual neuron is the hillock. However, the axon and body too are excited. In the axon hillock, the remaining potential is -70mV and the threshold potential is -55 MV. Synaptic inputs into the neuron trigger depolarization which causes the membrane potential to increase or decrease. Action potential is created when enough depolarization is accumulated and that membrane potential reaches the threshold.

Action potential is the outcome that voltage-gated ion channels found within the plasma membranes of cells. A voltage-gated ion canal is actually a cluster of proteins that remain embedded in the plasma membrane. It produces action potential as it may give rise to the positive feedback loop. Membrane potential is the main factor responsible for control of the activity of ion channels. Action potential is generated whenever the positive feedback runs at full speed. The time and the intensity are determined by the bio-physical properties of the ion channels with voltage-gated voltage. Several types of ion channels are known to produce positive feedback mechanisms and cause the creation of these potentials. Voltage-gated sodium channels play a role in the production of high-speed potentials that mimic those of nerve impulse. Slower ones , like those made in the muscles are controlled by the calcium Ion channels.The most researched voltage-gated ion channels are the sodium ion channels which are involved in quicker nerve impulse conduction.

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