Commissioner Gordon Action Figure
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Most cells have in a voltage differential between their environment and their inside. The voltage of a cell is measured in milli volts (mV). The voltage of a typical animal cell is around -70 mV. In the majority of cells no voltage fluctuations are known for their existence, but in some cells this is an expected characteristic. Cells can show oscillations between up and down when the voltage drops and increases. The duration of these potentials vary throughout a vast range. In brain cells the up and down cycles of action potentials are completed in less than a thousandth of a second. However, in other cells, sequences can take as long as a couple of seconds. The electrical properties of an animal cell is dependent upon the membrane structure. The cell membrane is composed of a layer of lipids and proteins. The lipid layer functions as an insulator.
Animal cells are all electrically polarized since they have an electric voltage which is called membrane potential. For cells, neurons and axons, dendrites and the body of the cell have distinct electrical properties. Most excitable portion of neuron is called the axon hillock however axons and the cell body can also be stimulated. At the axon , the threshold potential for resting is -70mV and the threshold potential is 55 MV. Neuronal synaptic interactions result in depolarization which causes membrane potential to rise or decrease. Action potentials are generated when enough depolarization occurs and the membrane's potential exceeds the threshold.
Action potential is the result of the activity of voltage-gated ion channels found within the plasma membrane of a cell. A voltage-gated , ion channel is actually a group consisting of proteins that stay in plasma membrane and produces action potential as it may produce the positive feedback loop. Membrane potential is the main factor responsible for managing the state of these channels. The action potential is created by the positive feedback cycle that gets full power. The frequency and duration are determined by the bio-physical properties of the ion-channels that are voltage-gated. A variety of Ion Channels are recognized that create positive feedback circuits that ultimately lead to the generation of these potentials. Voltage-gated sodium channel are involved in the creation of fast potentials that are similar to nerve impulses. More slow ones such as those produced by muscles cells are controlled by calcium ion channels.The the most intensely studied voltage-gated Ion channels are the sodium channels, which play a role in faster nerve impulse communication.
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