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Community Action Burlington Iowa


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An action potential occurs in which the membrane voltage of a particular cell increases but then decreases. It is a signature characteristic for a range of animal cells , including muscles, neurons, and endocrinological cells. Certain plant cells also produce them. Neurons play a vital role in cell-tocell communications. In the beta pancreas cells actions potential is associated with production of insulin. Plasma membranes comprise a particular kind of voltage-gated Ion channels producing action potential. The channels are closed at times when membrane potential is close to the resting potential of the cell but when the membrane's potential is increased then the channels become active. As the channels become open, they allow the flow of sodium ions. This increases the cell's membrane potency. The rapid inward flow of sodium ions affects the membrane's polarity and in turn, they turn off. The potassium channels then become activated and that is followed by an outward flow of the potassium ions . As a result, the membrane is returned back to its normal state. A transient positive shift known as refractory is a way to stop back forward motion of an action potential. In animal cells generally , two types of potentials are well-known, such as one that is generated because of voltage-gated sodium channels and the second that is generated by calcium channels that are voltage-gated.

Nearly all cells maintain in a voltage differential between their surroundings and their interior. The voltage of a cell is measured in milli volts (mV). The voltage of a typical animal cell is -70mV. In the majority of cells no voltage fluctuations are known for their existence, but in some cells, this is a common characteristic. Certain cells may also exhibit variations in the voltage, as they increase and decrease in voltage. The duration of these potentials vary throughout a vast range. In brain cells, the up and down cycles of action potentials are accomplished in less than one thousandth of a second. However, in other cells, the cycles can take up to a few seconds. The electrical characteristic of an animal cell is dependent upon the membrane structure. The cell membrane is composed of an lipid layer and proteins. The lipid layer functions as an insulator.

All animal cells are electrically polarized as they maintain the same voltage, also called membrane potential. For cells, neurons and axons, dendrites and the body of the cell have distinct electrical characteristics. One of the most exciting parts of a neuron is the axon hillock however axons and the cell body are also excited. At the axon , the resting voltage is -70 mV and the threshold is 55 MV. Synaptic connections to the nerve result in depolarization causing the membrane potential to increase or fall. It is produced when enough depolarization builds up until the membrane voltage reaches the threshold.

Action potential is the outcome of the activity of voltage-gated ion channels found within the plasma membranes of cells. A voltage-gated Ion Channel is actually a group made of proteins. They remain in plasma membrane and produces the action potential, which can be the cause of an positive feedback loop. Membrane power is responsible for control of the activity of Ion channels. Action potential is generated when the feedback cycle is carried out at full force. The duration and intensity are dependent on the bio-physical properties of the voltage-gated Ion Channels. Several types of ion channels have been identified which generate positive feedback cycles that eventually lead to the generation of these potentials. The sodium channels that are voltage-gated participate in the production of high-speed potentials similar to those generated by nerve impulses. They are slower than those that occur in muscle cells are mediated by the calcium Ion channels.The most intensively studied voltage-gated Ion channels are the sodium-ion channels that contribute to quicker nerve impulse conduction.

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