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Cactus Jack Action Figure


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Action potential refers to an event that causes the membrane potential for a specific cell initially increases then decreases. It is a common characteristic to a variety of animal cells namely, neurons, muscle cells and the endocrine cell. Plant cells can also produce these. Neurons play an extremely important function in cell-to-cell communication. In the beta pancreas cells action potentials are associated with the release of insulin. Plasma membranes contain a distinct type of ion channels that are voltage-gated for producing action potential. These channels are shut as long as the potential of the membrane is near that of the cell but when the membrane's potential increases and the channels begin to open, they become active. As the channels become open, they permit an inward flow sodium ions. This increases their membrane voltage. The swift inward flow of sodium ions causes a change in the membrane's polarity and in turn, they disappear. In the following, potassium channels become active and inward flows of the potassium ions , causing the membrane is returned back to its normal state. A transient , negative shift known as refractory is a way to stop back running of the action kinetic. In the animal cell, generally two kinds of these are understood, one of which is by voltage-gated sodium channels and another one that is caused by calcium channels that are voltage-gated.

Nearly all cells show in a voltage differential between their interior and exterior environment. The voltage of a cell is measured in milli volts (mV). The typical voltage for an animal cell is -70mV. Most cells have few voltage fluctuations are believed to occur , however in certain cells, this is a common characteristic. Cells can show oscillations between up and down when they increase and decrease in voltage. The duration of these voltages vary over a wide range. In brain cells the up and down process of action possible are completed in less than thousandth of a second, whereas in other cells, these intervals may be prolonged to several seconds. The electrical property of a cell in the animal kingdom is dependent on its membrane structure. Cell membrane is comprised of one layer of lipids along with proteins. The lipid layer acts as an insulation.

All animal cells are electrically polarized and maintain the voltage differential called membrane potential. For dendrites, neurons, axons and the cell body all have different electrical characteristics. One of the most exciting parts of an neuron is its axon hillock. However, axons and cells body are also excited. At the axon , the resting potential is -70 mV and the threshold potential is -55 mV. Synaptic stimulation to the neuron cause depolarization, causing the membrane potential to increase or fall. It is produced when enough depolarization occurs and that membrane potential reaches a threshold value.

Action potential is the outcome from the voltage-gated channels which are located within the plasma membrane of a cell. A voltage-gated ion channel is actually a cluster of proteins that are embedded in the plasma membrane. This produces actions potential due to the fact that it could be the cause of the positive feedback loop. Membrane potential plays a role in setting the parameters of these channels. Action potential is generated as the feedback loop goes on at full-speed. The time and the intensity are dependent on the bio-physical properties of the ion channel voltage-gated. There are a variety of ion channel types that are known that produce positive feedback cycles that eventually create these potentials. The sodium channels that are voltage-gated participate in the generation of higher-frequency potentials , similar to those that result from nerve impulse. In contrast, the slower ones produced by muscles are controlled by calcium Ion channels.The most thoroughly studied voltage-gated ion channels are the sodium ion channels participating in quicker nerve impulse conduction.

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