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The action potential is a process in which the potential of the membrane that a cell has first increases then decreases. It is a common characteristic of a number of living cells, including muscles, neurons, and cell types that are endocrine. Plant cells can also produce them. Neurons play a significant role in cell-to-cell communication. In beta cells of pancreas action potentials are connected to production of insulin. Plasma membrane is a type of voltage-gated ion channels for creating action potential. These channels are shut at times when membrane potential is close to those of the cell but when the membrane's voltage increases then the channels open. When the channels are inactive, they permit the inward flow of sodium ions, which increase the cell's membrane potency. The rapid inward flow of sodium ions result in changing the polarity of the membrane and consequently they become inactive. Following this, potassium channels become activated , and it is a flow of the potassium ions . As a result, the membrane returns to its resting state. A transient positive shift known as refractory periods prevents back forward motion of an action potential. In the cells of animals, generally two types of these potentials exist, acknowledged, one that is generated due to the voltage-gated sodium channels, and another that results from calcium channels that are voltage-gated.

The majority of cells have some degree of voltage variation between their internal and external environments. The voltage of a cell is measured in millivolts (mV). The typical voltage of an animal cell is around -70 mV. In most cells, tiny voltage fluctuations are observed to occur but in some cells this is a typical feature. Certain cells may also exhibit periodic up and down oscillations as the voltage rises and falls. The duration of these voltages can be varied over a broad spectrum. In brain cells the down and up cycles of action potentials are complete in less than the thousandth of a second while in other cells, these cycles could take several seconds. The electrical ability of an animal cell is influenced by the membrane structure. Cell membranes are composed of an lipid layer and proteins. The lipid layer functions as an insulation.

Animal cells are all electrically polarized and maintain a voltage difference called membrane potential. In case of neurons, , dendrites and cells have distinct electrical properties. The area that is most excitable in one's neuron's axon hillock. However, the axon and body also get excited. The axon hillock's resting potential is -70mV and the threshold voltage is at -55 millivolts. Synaptic stimulation to the neuron result in depolarization that causes the membrane potential to rise or fall. An action potential is created once sufficient depolarization takes place and that membrane potential reaches the threshold.

Action potential is the outcome in the function of voltage-gated channels found within the plasma membrane of a cell. A voltage-gated ion canal is in fact a collection of proteins that remain embedded in the plasma membrane. This produces an action potential since it could generate an positive feedback loop. Membrane potential is the main factor responsible for monitoring the status of Ion channels. Action potential is generated during the time that the feedback cycle takes place at full intensity. The time and amplitude are determined by the bio-physical properties of the ion-channels that are voltage-gated. There are a variety of ion channel types that are identified that generate positive feedback loops and eventually cause the creation of these potentials. The sodium channels with voltage are involved in the production of high-speed potentials that mimic those of nerve impulses. These are the ones that are slower, similar to those found in the muscles are controlled by calcium ion channels.The most studied voltage-gated Ion channels are sodium ion channels which are involved in faster nerve impulse conduction.

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