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Action potential refers to an event in which the membrane voltage that a cell has first increases but then decreases. It is a characteristic property to a variety of animals, including muscle cells, neuron cells, and Endocrine cells. Plant cells can also produce these. Neurons play an important function in cell-to-cell communication. In beta cells of pancreas action potentials are associated with that release of insulin. Plasma membranes feature a unique type of ion channels that are voltage-gated for producing action potential. They remain closed in the event that membrane potentials are near the resting potential of the cell . However, should the membrane potential increase then the channels will become active. When the channels are inactive, they allow an inward flow of sodium ions, which boosts the potential of membranes. The rapid flow of sodium ions affects the membrane's polarity and they stop functioning. After that potassium channels become active and it is a flow potassium ions . As a result, the membrane is returned to its normal state. A transient negative shift known as the refractory phase prevents the return forward motion of an action potential. In animal cells , usually two types of potentials are in existence, one of which is due to the voltage-gated sodium channels, the other is produced due to voltage-gated calcium channels.

A majority of cells experience the voltage of their internal and external environments. The cell's voltage is measured in milli volts (mV). The typical voltage of an animal cell is around -70 mV. In majority of cells very minimal voltage fluctuations have been observed to occur but in some cells, this is a standard feature. Certain cells can also exhibit oscillations between up and down when the voltage decreases and increases. The duration of these voltages vary over a wide range. In brain cells the up and down cycles of action potentials are executed in less then a thousandth of a second. In other cell types, the sequences can take as long as a couple of seconds. The electrical property of a cell in the animal kingdom is influenced by the membrane structure. Cell membrane is comprised of two layers of lipids and proteins. The lipid layer functions as an insulator.

Animal cells are all electrically polarized . They maintain a voltage variation called membrane potential. For the neurons, dendrites and the cell body all have different electrical properties. The most stimulated part of neuron is the axon hillock, however the axon as well as the cell body also get excited. At the axon , the resting potential is -70 mV and the threshold voltage is 55 mV. Synaptic inputs into the neuron result in depolarization that causes the membrane potential to increase or fall. Action potentials are produced when enough depolarization occurs and the membrane current reaches a threshold value.

The action potential results of activity of voltage-gated ion channels present in the plasma membranes of cells. A voltage-gated ion canal is in fact a collection of proteins that are embedded in plasma membrane and produces an action potential since it could cause positive feedback loop. Membrane potential is accountable for maintaining the state of the Ion channels. The action potential is created whenever the positive feedback goes on at full-speed. The frequency and duration are dependent on the bio-physical properties of the voltage-gated ion channels. Many types of ion channels are available that are believed to generate positive feedback cycles , which eventually cause the creation of these potentials. The sodium channels with voltage are involved in the generation of larger impulses like nerve impulses. Slower ones , like those made in the muscles cells are controlled by the calcium Ion channels.The most researched voltage-gated Ion channels are sodium channels, which play a role in faster nerve impulse communication.

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