Harley Quin Action Figure
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Nearly all cells maintain an electrical difference between their exterior and interior environments. The voltage of a cell is measured in milli volts (mV). The typical voltage for an animal cell is around -70 mV. In the majority cells, small voltage fluctuations are reported to occur but in some cells this is an expected feature. Some cells exhibit variations in the voltage, as the voltage drops and increases. The time between these potentials fluctuate over a large range. In brain cells, the up and down cycle of action potential are completed in less than a thousandth of a second, whereas in different types of cells, the processes can last several seconds. The electrical activity of a cell in the animal kingdom depends on the membrane structure. The cell membrane is composed of layers of lipids, and proteins. The lipid layer functions as an insulator.
All animal cells are electrically polarized and maintain the same voltage, also called membrane potential. For dendrites, neurons, axons as well as the cell body have various electrical characteristics. The area that is most excitable in a neuron is the axon hillock but axon and cell body can also be excited. The axon hillock's threshold potential for resting is -70mV and the threshold potential is at -55 millivolts. Synaptic stimulation to the neuron cause depolarization, causing the membrane potential to increase or fall. An action potential is created once enough depolarization occurs and the membrane's potential exceeds the threshold.
The action potential results of the work of voltage-gated Ion channels within the plasma membrane of cells. The voltage-gated channel is actually a group of proteins which remain in the plasma membrane. It generates actions potential due to the fact that it could be the cause of a positive feedback loop. Membrane potential is the main factor responsible for control of the activity of these channels. The action potential is created when the positive feedback cycle goes on at full-speed. The duration and intensity are controlled by the bio-physical characteristics of the ion channels that are voltage-gated. A variety of Ion Channels are known that produce positive feedback mechanisms and create these potentials. Voltage-gated sodium-channels are involved in the generation of larger potentials that mimic those of nerve impulses. Slower ones like those produced in muscle cells are mediated by the calcium Ion channels.The most thoroughly studied voltage-gated channel are sodium ion channels that are involved in greater speed of nerve impulse conduction.
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