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Action potential refers to an event that occurs when the membrane potential of a living cell first increases then decreases. It is a signature characteristic and characteristic of a lot of animal cells namely, muscles cells, neurons and cell types that are endocrine. Plant cells also produce them. Neurons play an important role in cell-tocell communications. In beta cells of pancreas the action potential is associated with that release of insulin. Plasma membranes have a specific type in voltage-gated, ion-channels that are used for producing action potential. They remain closed as long as the potential of the membrane is close to it's resting value of the cell . However, when the membrane potential rises then the channels become active. When the channels are inactive, they allow for an inward flow sodium ions, which increase its membrane potential. The rapid inward flow sodium ions affects the membrane's polarity and consequently they turn off. The potassium channels then become activated and they are able to flow outward potassium ions , causing the membrane is returned back to its normal state. A transient negative shift , also known as refractory time prevents the back motion of the potential. In animal cells , typically two types of these potentials exist, described, for instance, one of which is created by the voltage-gated calcium channels, and another that results from calcium channels that are voltage-gated.

Most cells have in a voltage differential between their external and internal environments. The voltage of the cell is measured in millivolts (mV). The typical voltage for an animal cell is around -70 mV. In majority of cells very low voltage variations are thought as occurring, however in certain cells, this is a common characteristic. Cells can show up and down cycles as the voltage goes up and down. The duration of these voltages vary over a wide range. In brain cells, the up and down process of action possible are completed in less than thousandth of a second, whereas in other cells, the processes can last several seconds. The electrical capacity of an animal cell is dependent on the membrane structure. The cell membrane is composed of layers of lipids and proteins. The lipid layer serves as an insulation.

Animal cells are all electrically polarized since they have a voltage variation known as membrane potential. In case of the neurons, dendrites and cells' bodies possess distinct electrical properties. The most excitable part of neuron is the Axon hillock but axon and cell body can also be stimulated. The axon hillock's resting potential is -70 mV and the threshold potential is at -55 mgV. Synaptic connections to the nerve cause depolarization, causing the membrane potential to increase or decrease. It is produced when enough depolarization has occurred and the membrane potential reaches the threshold.

Action potential is the result on the activities of voltage-gated channels within the plasma membranes of cells. A voltage-gated ion channel is actually a group of proteins which remain in the plasma membrane. This produces action potential as it may create an positive feedback loop. Membrane potential is responsible for control of the activity of ion channels. The action potential is created as the feedback loop is carried out at full force. The time and amplitude are controlled by the bio-physical characteristics of the voltage-gated ion channels. Many types of ion channels are known that produce positive feedback cycles , which eventually lead to the generation of these potentials. Voltage-gated sodium channels are involved with the creation of higher possibles that resemble those produced by nerve impulse. The slower ones, like those generated in the muscles cells are controlled by the calcium Ion channels.The most extensively studied voltage-gated Ion channels are the sodium-ion channels that contribute to higher speed nerve impulse transmission.

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